學術成大
學術論文

1. Tsung-Ming Chang^†, Wei-Yu Fang^†, Hui-Ping Hsu^†, Pei-Yi Chu, Shih-Sheng Jiang, Kuo-Wei Huang, Wen-Chun Hung, Hui-You Lin, Hui-Jen Tsai*. PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-β/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquitination. Cancer Biol Ther 2025 Dec; 26(1): 2478670. (SCI, co-first author)
2. Pei-An Fu, Ya-Chun Hsu, Hui-Ping Hsu, Tzu-Chien Lin, Wei-Pang Chung*. Premenopausal patients with clinically aggressive metastatic breast cancer successfully treated with a first-line palbociclib-containing regimen: two cases and literature review. Cancer Rep (Hoboken) 2025 Dec; 8(12): e70417. (ESCI, case report)
3. I-Sung Chen^†, Chi-Che Hsieh^†, Chun-Chun Li, You-Lin Wei, Chao-Chun Cheng, Sheng-Wei Feng, Hsin-Lun Lee, Nai-Jung Chiang*, Che-Hung Shen*, Hui-Ping Hsu*. ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer. Oncogenesis 2025 Nov 21; 14(1): 45.(SCI, co-corresponding author).
4. Cheng-Han Lee, I-Sung Chen, Ying-Jui Chao, Hui-Ping Hsu*. High plasma histidine concentration predicts a favorable prognosis in patients with ampullary cancer. Am J Cancer Res 2025 Oct; 15(10): 4452-4469. (SCI, corresponding author).
5. Tzu-Hui Wei, Chi-Che Hsieh, Zhu-Jun Loh, Wei-Pang Chung, Kuo-Ting Lee, Yi-Ling Chen*, Hui-Ping Hsu*, Che-Hung Shen*. Suppression of STK11 induces expansion of polymorphonuclear myeloid-derived suppressive cells and activation of immune signaling in breast cancer. Cancer Immunol Immunother 2025 Oct 6;74(11):328. (SCI, co-corresponding author)
6. Yu-Ling Hsu, Chun-Hui Lee, Wei-Pang Chung, Wen-Huang Lee, Kuo-Ting Lee, Jui-Hung Tsai, Hui-Ping Hsu, Shuen-Ru Yang, Zhu-Jun Loh, Pei-Fang Su, Chao-Ming Hung, Wei-Chuan Tsai, Yen-Wen Liu, Ping-Yen Liu. Primary cardioprotective effect of sacubitril/valsartan in breast cancer patients receiving adjuvant therapy. Eur J Heart Fail 2025 Nov;27(11):2141-2151.
7. You-Yu Liu, Wei-Lun Huang, Sin-Tian Wang, Hui-Ping Hsu, Tzu-Ching Kao, Wei-Pang Chung*, Kung-Chia Young*. CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells. Cancer Metab. 2025 Feb 7;13(1):6.
8. Han-Kun Chen, Yi-Ling Chen, Wei-Pang Chung, Zhu-Jun Loh, Kuo-Ting Lee, Hui-Ping Hsu*. Circulating CD3⁺CD8⁺ T lymphocytes as indicators of disease status in patients with early breast cancer. Cancer Med 2025 Jan; 14(1): e70547. (SCI, corresponding author)
9. Kuo-Ting Lee, Dao-Peng Chen, Zhu-Jun Loh, Wei-Pang Chung, Chih-Yang Wang, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Hui-Ping Hsu*. Benign polymorphisms in the BRCA genes with linkage disequilibrium is associated with cancer characteristics. Cancer Sci 2024 Dec; 115(12): 3973-3985. (SCI, corresponding author)
10. Han-Kun Chen, Yi-Ling Chen, Chih-Yang Wang, Wei-Pang Chung, Jung-Hua Fang, Ming-Derg Lai, Hui-Ping Hsu*. ABCB1 regulates immune genes in breast cancer. Breast Cancer – Targets Ther (Dove Med Press) 2023 Nov 13; 15: 801-811. (SCI, corresponding author)
11. Chih-Yang Wang, Do Thi Minh Xuan, Pei-Hsuan Ye, Chung-Yen Li, Gangga Anuraga, Hoang Dang Khoa Ta, Ming-Derg Lai, Hui-Ping Hsu*. Synergistic suppressive effects on triple-negative breast cancer by the combination of JTC-801 and sodium oxamate. Am J Cancer Res 2023 Oct 15; 13(10): 4661-4677. (SCI, corresponding author)
12. Chung-Yen Li, Gangga Anuraga, Chih-Peng Chang, Tzu-Yang Weng, Hui-Ping Hsu, Hoang Dang Khoa Ta, Pei-Fang Su, Pin-Hsuan Chiu, Shiang-Jie Yang, Feng-Wei Chen, Pei-Hsuan Ye, Chih-Yang Wang, Ming-Derg Lai. Repurposing nitric oxide donating drugs in cancer therapy through immune modulation. J Exp Clin Cancer Res 2023 Jan 14; 42(1): 22. (SCI)
13. Do Thi Minh Xuan, Chung-Che Wu, Wei-Jan Wang, Hui-Ping Hsu, Hoang Dang Khoa Ta, Gangga Anuraga, Chung-Chieh Chiao, Chih-Yang Wang. Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. Int J Med Sci 2023 Jan 1; 20(1): 35-49. (SCI)
14. Hui-Ping Hsu, Pei-Yi Chu, Tsung-Ming Chang, Kuo-Wei Huang, Wen-Chun Hung, Shih Sheng Jiang, Hui-You Lin, Hui-Jen Tsai*. Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor-positive breast cancer via regulation of the mTOR pathway. Cancer Med. 2023 Jan; 12(2): 1588-1601. (SCI, co-first authors)
15. Wei-Pang Chung, Wei-Lun Huang, Chun-Hui Lee, Hui-Ping Hsu, Wan-Ling Huang, You-Yu Liu, Wu-Chou Su*. PI3K inhibitors in trastuzumab-resistant HER2-positive breast cancer cells with PI3K pathway alterations. Am J Cancer Res 2022 Jul 15; 12(7): 3067-3082. (SCI)
16. Yi-Ling Chen, Kuo-Ting Lee, Chih-Yang Wang, Che-Hung Shen, Sheau-Chiann Chen, Wei-Pang Chung, Ya-Ting Hsu, Yao-Lung Kuo, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Meng-Ru Shen, Hui-Ping Hsu*. Low expression of cytosolic NOTCH1 predicts poor prognosis of breast cancer patients. Am J Cancer Res 2022 May 15; 12(5): 2084-2101. (SCI, corresponding author)
17. Pang-Shuo Perng, Hui-Ping Hsu, Po-Hsuan Lee, Chi-Chen Huang, Chien-Chung Lin, Jung-Shun Lee. Correlation of EGFR mutation subtypes and survival in surgically treated non-small cell lung cancer brain metastasis. Asian J Surg. 2023 Jan;46(1):269-276. (SCI)
18. Yi-Ling Chen, Chih-Yang Wang, Jung-Hua Fang, Hui-Ping Hsu*. Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness. Am J Cancer Res. 2021 Sep 15; 11(9): 4277-4293. (SCI, corresponding author)
19. Peng-Chan Lin, Yu-Min Yeh, Hui-Ping Hsu, Ren-Hao Chan, Bo-Wen Lin, Po-Chuan Chen, Chien-Chang Pan, Keng-Fu Hsu, Jenn-Ren Hsiao, Yan-Shen Shan, Meng-Ru Shen*. Comprehensively exploring the mutational landscape and patterns of genomic evolution in hypermutated cancers. Cancers (Basel) 2021 Aug 26; 13(17): 4317. (SCI)
20. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells. J Microbiol Immunol Infect 2021 Oct; 54(5): 845-857. (SCI, co-corresponding author)
21. Zhu-Jun Loh, Kuo-Ting Lee, Ya-Ping Chen, Yao-Lung Kuo, Wei-Pang Chung, Ya-Ting Hsu, Chien-Chang Huang, Hui-Ping Hsu*. False-Negative frozen section of sentinel nodes in early breast cancer (cT1-2N0) patients. World J Surg Oncol 2021; 19(1): 183. (SCI, corresponding author)
22. Li-Chin Cheng, Tzu-Jen Kao, Nam Nhut Phan, Chung-Chieh Chiao, Meng-Chi Yen, Chien-Fu Chen, Jui-Hsiang Hung, Jia-Zhen Jiang, Zhengda Sun, Chih-Yang Wang*, Hui-Ping Hsu*. Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease. Medicine 2021; 100(7): e24321 (SCI, co-corresponding author)
23. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Hsin-Liang Liu, Chih-Yang Wang*, Hui-Ping Hsu*. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis. Int J Med Sci 2021; 18(5): 1143-1152. (SCI, co-corresponding author)
24. Wei-Pang Chung, Kuo-Ting Lee, Ya-Ping Chen, Ya-Ting Hsu, Zhu-Jun Loh, Chien-Chang Huang, Hui-Ping Hsu*. The prognosis of early-stage breast cancer in extremely young female patients in a single institute. Medicine 2021; 100(1): e24076. (SCI, corresponding author)
25. Pin-Shern Chen^†, Hui-Ping Hsu^†, Nam Nhut Phan, Meng-Chi Yen, Feng-Wei Chen, Yu-Wei Liu, Fang-Ping Lin, Sheng-Yao Feng, Tsung-Lin Cheng, Pei-Hsiang Yeh, Hany A Omar, Zhengda Sun, Jia-Zhen Jiang, Yi-Shin Chan, Ming-Derg Lai, Chih-Yang Wang*, Jui-Hsiang Hung*. CCDC167 as a potential therapeutic target and regulator of cell cycle-related networks in breast cancer. Aging-US 2021; 13(3): 4157-4181. (SCI, co-first authors)
26. Chih-Yang Wang, Ying-Jui Chao, Yi-Ling Chen, Tzu-Wen Wang, Nam Nhut Phan, Hui-Ping Hsu*, Yan-Shen Shan, Ming-Derg Lai. Upregulation of peroxisome proliferator-activated receptor-α and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer. Int J Med Sci 2021; 18(1): 256-269. (SCI, corresponding author)
27. Li-Chin Cheng, Ying-Jui Chao, Michael J. Overman, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yan-Shen Shan*, Ming-Derg Lai. Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence. Sci Rep 2020; 10: 13255. (SCI, co-corresponding authors)
28. Li-Chin Cheng, Ying-Jui Chao, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yih-Jyh Lin, Yan-Shen Shan*, Ming-Derg Lai. Cancer-derived transforming growth factor-b modulates tumor-associated macrophages in ampullary cancer. OncoTargets Ther 2020; 13: 7503-7516. (SCI, co-corresponding authors)
29. Yi-Yi Lin, Chih-Yang Wang, Nam Nhut Phan, Chung-Chieh Chiao, Chung-Yen Li, Zhengda Sun, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Hui-Ping Hsu*, Ming-Derg Lai*. PODXL2 maintains cellular stemness and promotes breast cancer development through the Rac1/Akt pathway. Int J Med Sci 2020; 17(11): 1639-1651. (SCI, co-corresponding authors)
30. Hsin-Liang Liu, I-Jeng Yeh, Nam Nhut Phan, Yen-Hung Wu, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Jia-Zhen Jiang, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models. Infect Genet Evol 2020; 104438. (SCI, co-corresponding authors)
31. Nam Nhut Phan, Shirui Liu, Chih-Yang Wang, Hui-Ping Hsu, Ming-Derg Lai, Chung-Yen Li, Chien-Fu Chen, Chung-Chieh Chiao, Meng-Chi Yen, Zhengda Sun, Jia-Zhen Jiang*. Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database. Int J Clin Exp Pathol 2020; 13(5): 1220-1242. (SCI, co-first authors)
32. Chih-Yang Wang, Chung-Chieh Chiao, Nam Nhut Phan, Chung-Yen Li, Zheng-Da Sun, Jia-Zhen Jiang, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Hui-Ping Hsu*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer. Am J Cancer Res 2020; 10(1): 95-113. (SCI, co-corresponding authors)
33. Hui-Ping Hsu, Chih-Yang Wang, Pei-Yin Hsieh, Jung-Hua Fang, Yi-Ling Chen*. Knockdown of serine/threonine-protein kinase 24 promotes tumorigenesis and myeloid-derived suppressor cell expansion in an orthotopic immunocompetent gastric cancer animal model. J Cancer 2020; 11(1): 213-228. (SCI, first author)
34. Chih-Yang Wang, Yung-Chieh Chang, Yao-Lung Kuo, Kuo-Ting Lee, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Nam Nhut Phan, Meng-Ru Shen, Hui-Ping Hsu*. Mutation of the PTCH1 gene predicts recurrence of breast cancer. Sci Rep 2019; 9: 16359.1-1639.14. (SCI, corresponding author)
35. Chia-Yi Su, Ruei-Liang Yan, Wen-Hsin Hsu, Ching-Tung Chu, Hsuan-Chia Chang, Chien-Chen Lai, Hui-Ping Hsu, Hong-Chen Chen*. Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Sci Rep 2019; 9(1): 13703.e1-13703.e11. (SCI)
36. Wei-Pang Chung, Ya-Tin Hsu, Ya-Ping Chen, Hui-Ping Hsu*. Treatment of a patient with breast cancer and glucose 6-phosphate dehydrogenase deficiency: a case report. Medicine 2019; 98(13): e14987.1-e14987.3. (SCI, corresponding author)
37. Tsung-Han Yang, Jen-Lung Chen, Yih-Jyh Lin, Ying-Jui Chao, Yan-Shen Shan, Hui-Ping Hsu, Zhe-Min Su, Chung-Ching Chou, Yi-Ting Yen*. Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes. Surg Endosc 2018; 32(10): 4314-4320. (SCI)
38. Tzu-Yang Weng, Hsuan Franziska Wu, Chung-Yen Li, Yu-Hsuan Hung, Yu-Wei Chang, Yi-Ling Chen, Hui-Ping Hsu, Yu-Hung Chen, Chih-Yang Wang, Jang-Yang Chang, Ming-Derg Lai*. Homoharringtonine induced immune alteration for an efficient anti-tumor response in mouse models of non-small cell lung adenocarcinoma expressing Kras Mutation. Sci Rep 2018; 8(1): 8216. (SCI)
39. Tzu-Yang Weng, Chia-Jung Li, Chung-Yen Li, Yu-Hsuan Hung, Meng-Chi Yen, Yu-Wei Chang, Yu-Hung Chen, Yi-Ling Chen, Hui-Ping Hsu, Jang-Yang Chang, Ming-Derg Lai*. Skin delivery of Clec4a small hairpin RNA elicited an effective antitumor response by enhancing CD8⁺ immunity in vivo. Mol Ther Nucleic Acids. 2017; 9: 419-427. (SCI)
40. Chih-Yang Wang, Chung-Yen Li, Hui-Ping Hsu, Chien-Yu Cho, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Yu-Hsuan Hung, Kuo-Ting Lee, Jui-Hsiang Hung, Yi-Ling Chen, Ming-Derg Lai*. PSMB5 plays a dual role in cancer development and immunosuppression. Am J Cancer Res 2017; 7(11): 2103-2120. (SCI)
41. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Yu-Hsuan Hung, Chih-Yang Wang, Meng-Chi Yen, Yi-Ling Chen*. Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer. Oncol Lett. 2017 Oct; 14(4): 4517-4526. doi: 10.3892/ol.2017.6736. (SCI, co-first authors)
42. Hui-Ping Hsu, Ming-Derg Lai, Jenq-Chang Lee, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Jung-Hua Fang, Yi-Ling Chen*. Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling. Sci Rep. 2017 Jul 19; 7(1): 5823.e1-5823.e14. (SCI, first author)
43. Zhu-Jun Loh, Kuo-Ting Lee, Wei-Pang Chung, Wen-Chung Chen, Hsueh-Li Kuo, Po-Jun Chen, Hsi-Huei Lu, Hui-Ping Hsu*. Invasive lobular carcinoma of the breast with synchronous colon metastasis. Formosan J Surg 2017 Apr; 50(2): 69-73. (Corresponding author)
44. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai*. Silencing of argininosuccinate lyase inhibits colorectal cancer formation. Oncol Rep. 2017 Jan; 37(1): 163-170. (SCI)
45. Wei-Ching Chen, Hui-Ping Hsu, Yu-Hsuan Hung, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, and Ming-Derg Lai*. Cancer stem cell marker CD90 inhibits the ovarian cancer formation via β3 integrin. Int J Oncol. 2016 Nov; 49(5): 1881-1889. (SCI)
46. Ming-Jenn Chen, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Ming-Derg Lai. The membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia. Oncology Reports, 2016 Oct; 36(4): 1997-2008. (SCI, corresponding author)
47. Chih-Ming Su, Ting-Yu Chang, Hui-Ping Hsu, Hui-Huang Lai, Jie-Ning Li, Yu-Jhen Lyu, Kuang-Tai Kuo, Ming-Te Huang, Jen-Liang Su, Pai-Sheng Chen*. A novel application of E1A in combination therapy with EGFR-TKI treatment in breast cancer. Oncotarget. 2016 Sep 27; 7(39): 63924-63936. (SCI)
48. Chien-Yu Cho, Kuo-Ting Lee, Wei-Ching Chen, Chih-Yang Wang, Yung-Sheng Chang, Hau-Lun Huang, Hui-Ping Hsu, Meng-Chi Yen, Ming-Zong Lai, Ming-Derg Lai*. MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer. Oncotarget. 2016 Feb 20; 7(6). (SCI)
49. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai*. Argininosuccinate lyase is a potential therapeutic target in breast cancer. Oncology Reports 2015 Dec; 34(6): 3131-3139. (SCI)
50. Yan-Shen Shan, Yi-Ling Chen, Ming-Derg Lai, Hui-Ping Hsu*. Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer. Oncology Reports 2015 Dec; 33(1): 40-48. (SCI, corresponding author)
51. Wei-Ching Chen, Yung-Sheng Chang, Hui-Ping Hsu, Meng-Chi Yen, Hau-Lun Huang, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, Po-Ting Lai, Ching-Shih Chen, Yih-Jyh Lin, Ming-Derg Lai*. Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer. Oncotarget 2015 Dec 15; 6(40): 42923-42937. (SCI)
52. Cheng-Lin Wu, Ying-Jui Chao, Ta-Ming Yang, Yi-Ling Chen, Kung-Chao Chang, Hui-Ping Hsu*, Yan-Shen Shan, Ming-Derg Lai. Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44v is an indicator for recurrence in advanced cancer. BMC Cancer 2015 Nov 16; 15(1): 903.e1-903.e10. (SCI, corresponding author)
53. Ting-Wei Lin, Hui-Ping Hsu*. Increased activity of factor VIII causing acute intestinal ischemic disorder with recurrent and multiple arterial thromboses. Formosan J Surg 2015 Oct; 48(5): 177-180. (Corresponding author)
54. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Wei-Ching Chen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen*. Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines. Scientific Reports 2015 Apr 30; 5: 9783.e1-9783.e10. (SCI, co-first authors)
55. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Yi-Pey Luo, Yi-Ling Chen*. Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer. Oncology Reports 2015 Jan; 33(1): 49-57. (SCI, co-first authors)
56. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen*. Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model. Oncology Reports 2014 Dec; 32(6): 2335-2342. (SCI, co-first authors)
57. Ying-Jui Chao, Edgar D Sy, Hui-Ping Hsu, Yan-Shen Shan*. Predictors for resectability and survival in locally advanced pancreatic cancer after gemcitabine based neoadjuvant therapy. BMC Surgery 2014 Sep 25; 14(9): 72.e1-72.e8. (SCI)
58. Yu-Hsuan Hung, Yi-Shin Chan, Yung-Sheng Chang, Kuo-Ting Lee, Hui-Ping Hsu, Meng-Chi Yen, Wei-Ching Chen, Chih-Yang Wang, Ming-Derg Lai*. Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma. Oncology Reports 2014 Jun; 31(6): 2797-2803. (SCI)
59. Hau-Lun Huang, Hui-Ping Hsu, Shu-Chu Shieh, Yung-Sheng Chang, Wei-Ching Chen, Chien-You Cho, Chiao-Fang Teng, Ih-Jen Su, Wen-Chun Hung, Ming-Derg Lai*. Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide. Mol Cancer Ther. 2013 Nov; 12(11): 2505-2516. (SCI)
60. Yao-Lung Kuo, Wen-Chung Chen, Wei-Jen Yao, Lili Cheng, Hui-Ping Hsu, Hung-Wen Lai, Shou-Jen Kuo, Dar-Ren Chen*, Tsai-Wang Chang*. Validation of Memorial Sloan-Kettering Cancer Center nomogram for prediction of non-sentinel lymph node metastasis in sentinel lymph node positive breast cancer patients an international comparison. Int J Surg 2013 Aug; 11(7): 538-543. (SCI)
61. Yan-Shen Shan, Jung-Hua Fang, Ming-Derg Lai, Meng-Chi Yen, Pin-Wen Lin, Hui-Ping Hsu, Chian-Yuh Lin, Yi-Ling Chen*. Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules. Mol Carcinog 2011 Oct; 50(10): 739-750. (SCI)
62. I-Wen Lee, Lin Kang, Hui-Ping Hsu, Pao-Lin Kyo, Chia-Ming Chang*. Puerperal mastitis requiring hospitalization during a nine-year period. Am J Obstet Gynecol 2010 Oct; 203(4): 332.e1-e6. (SCIE)
63. Te-Ling Lu, Guan-Jhong Huang, Huang-Joe Wang, Jian-Lian Chen, Hui-Ping Hsu, Te-Jung Lu*. Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy. Biochem Biophys Res Commun 2010 Jul; 398(1): 26-31. (SCI)
64. Hui-Ping Hsu, Yan-Shen Shan, Ming-Derg Lai, Pin-Wen Lin*. Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival. Cancer Biol Ther 2010 Jul 15; 10(2): 144-154. (SCI, first author)
65. Hui-Ping Hsu, Yan-Shen Shan, Pin-Wen Lin*, Ying-Tai Jin, Ming-Derg Lai. Loss of E-cadherin and b-catenin is correlated with poor prognosis of ampullary neoplasms. J Surg Oncol 2010 Apr 1; 101(5): 356-362. (SCI, first author)
66. Hui-Ping Hsu. Prognosis of ampullary carcinoma after radical resection and its carcinogenesis. Formos J Surg 2008 Dec; 41(6): 257-261. (Mini Review)
67. Hui-Ping Hsu, Yan-Shen Shan*, Yu-Hsiang Hsieh, Ta-Ming Yang, Pin-Wen Lin. Predictors of recurrence after pancreaticoduodenectomy in ampullary cancer: comparison between non-, early and late recurrence. J Formos Med Assoc 2007 Jun; 106(6): 432-443. (SCI, first author)
68. Paul J. Karanicolas*, Edward Davies, Regina Kunz, Matthias Briel, H. Pavan Koka, Darrin M. Payne, Shona E. Smith, Hui-Ping Hsu, Pin-Wen Lin, Christian Bloechle, Karl-Joseph Paquet and Gordon H. Guyatt. The pylorus: take it or leave it? Systemic review and meta-analysis of pylorus-preserving versus standard Whipple pancreaticoduodenectomy for pancreatic or periampullary cancer. Ann Surg Oncol 2007 Jun; 14(6): 1825-1834. (SCI)
69. Hui-Ping Hsu, Ta-Ming Yang, Yu-Hsiang Hsieh, Yan-Shen Shan*, Pin-Wen Lin. Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. Ann Surg Oncol 2007 Jan; 14(1): 50-60. (SCI, first author)
70. Hui-Ping Hsu, Yan-Shen Shan*, Yu-Hsiang Hsieh, Edgar D. Sy, Pin-Wen Lin. Impact of Etiologic factors and APACHE II and POSSUM scores in management and clinical outcome of acute intestinal ischemic disorders after surgical treatment. World J Surg 2006 Dec; 30(12): 2152-2162. (SCI, first author)
71. Hui-Ping Hsu, Yan-Shen Shan, Edgar D. Sy, Pin-Wen Lin*. Acute mesentery venous occlusion in patients with warfarin – warfarin therapy may complicate the diagnosis of intestinal vascular complication. Formosan J Surgery 2005 Feb; 38(1): 13-19. (First author)
72. Yan-Shen Shan, Hui-Ping Hsu, Yu-Hsiang Hsieh, Edgar D. Sy, Jenq-Chang Lee, Pin-Wen Lin*. The significance of intraoperative peritoneal fungus culture in perforated peptic ulcer. Br J Surg 2003 Oct; 90: 1215-9. (SCI)
73. Hui-Ping Hsu, Pao-Lin Kuo*, Meng-Hsing Wu, Ta-Jen Wu, Yuan-Chang Dai, Ching-Cherng Tzeng, Shio-Jean Lin. Microscopic gonadoblastoma in a patient with 46,XY gonadal dysgenesis. Taiwanese J Obstet Gynecol 2001; 40: 77-81. (SCI, first author)
74. Nina Tsao, Hui-Ping Hsu, Ching-Ming Wu, Ching-Chuan Liu, Huan-Yao Lei*. TNF causes an increase in blood-brain barrier permeability during sepsis. J Med Microbiol 2001 Sep; 50(9): 812-821. (SCI)
75. Nina Tsao, Hui-Ping Hsu, Huan-Yao Lei*. TNFalpha-induced cyclooxygenase-2 not only increases the vasopermeability of blood-brain barrier but also enhances the neutrophil survival in Escherichia coli-induced brain inflammation. Prostaglandins & Other Lipid Mediators. 1999 Jul; 57(5-6): 371-382. (SCI)